Package	Price	Per Item	Savings	Order
	Glucophage 90 pills x 850 mg	$43.41	$0.48	$0

Glucophage
	Glucophage is used for treating type 2 diabetes.

Drug Name

Glucophage (Metformin)

Drug Uses

Glucophage is used for treating type 2 diabetes. It is used along with diet and exercise. It may be used alone or with other antidiabetic medicines.

How to use

Use Glucophage as directed by your doctor. Check the label on the medicine for exact dosing instructions.
An extra patient leaflet is available with Glucophage . Talk to your pharmacist if you have questions about this information.
Take Glucophage by mouth with food.
Take Glucophage on a regular schedule to get the most benefit from it. Taking Glucophage at the same time each day will help you remember to take it.
Continue to take Glucophage even if you feel well. Do not miss any doses.

Drug Class and Mechanism

Glucophage is a biguanide antidiabetic. It works by decreasing the amount of sugar that the liver produces and the intestines absorb. It also helps to make your body more sensitive to the insulin that you naturally produce.

Missed Dose

If you miss a dose of Glucophage , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Storage

Store at room temperature between 20-25 degrees C (68-77 degrees F).

Warnings/Precautions

Do NOT use Glucophage if:

• you are allergic to any ingredient in Glucophage
• you have congestive heart failure that is treated by medicine
• you have a severe infection, low blood oxygen levels, kidney or liver problems, high blood ketone or acid levels (eg, diabetic ketoacidosis), or severe dehydration
• you have had a stroke or a recent heart attack, or you are in shock
• you are 80 years old or older and have not had a kidney function test
• you will be having surgery or certain lab procedures

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Glucophage . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of heart problems (eg, heart failure), lung or breathing problems, thyroid problems, stomach or bowel problems (eg, paralysis, blockage), adrenal or pituitary problems, or lactic acidosis
• if you have vomiting, diarrhea, poor health or nutrition, low blood calcium or vitamin B12 levels, or anemia, or if you are dehydrated
• if you have an infection, fever, recent injury, or moderate to severe burns
• if you drink alcohol or have a history of alcohol abuse
• if you will be having surgery or certain lab procedures
• if you take a beta-blocker (eg, propranolol)

Some MEDICINES MAY INTERACT with Glucophage . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Amiloride, cimetidine, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, or vancomycin because they may increase the risk of Glucophage ’s side effects
• Calcium channel blockers (eg, nifedipine), corticosteroids (eg, prednisone), diuretics (eg, furosemide, hydrochlorothiazide), estrogen, hormonal contraceptives (eg, birth control pills), insulin, isoniazid, nicotinic acid, phenothiazine (eg, chlorpromazine), phenytoin, sulfonylureas (eg, glipizide), sympathomimetics (eg, albuterol, pseudoephedrine), or thyroid hormones (eg, levothyroxine) because the risk of high or low blood sugar may be increased

Possible Side Effects

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

• Diarrhea; gas; headache; indigestion; nausea; stomach upset; temporary metallic taste; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

• Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain or discomfort; dizziness or lightheadedness; fast or difficult breathing; feeling of being unusually cold; fever, chills, or persistent sore throat; general feeling of being unwell; muscle pain or weakness; slow or irregular heartbeat; unusual drowsiness; unusual or persistent stomach pain or discomfort; unusual tiredness or weakness.

More Information

If you have any questions about Glucophage , please talk with your doctor, pharmacist, or other health care provider.
Glucophage is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

Glucophage
		Glucophage 90 pills x 850 mg	$43.41

	Package	Price	Per Item	Savings	Order
	ActoPlus Met 30 pills x 500 mg	$49.83	$1.66	$0
	ActoPlus Met 60 pills x 500 mg	$87.12	$1.45	$13
	ActoPlus Met 90 pills x 500 mg	$118.29	$1.31	$31

ActoPlus Met
	Actoplus Met is used for treating type 2 diabetes.

Drug Name

Actoplus Met (Pioglitazone/Metformin)

Drug Uses

Actoplus Met is used for treating type 2 diabetes. It is used along with diet and exercise. It may be used alone or with other antidiabetic medicines.

How to use

Use Actoplus Met as directed by your doctor. Check the label on the medicine for exact dosing instructions.
An extra patient leaflet is available with Actoplus Met . Talk to your pharmacist if you have questions about this information.
Take Actoplus Met by mouth with meals.
Take Actoplus Met on a regular schedule to get the most benefit from it. Taking Actoplus Met at the same times each day will help you remember to take it.
Continue to take Actoplus Met even if you feel well. Do not miss any doses.

Drug Class and Mechanism

Actoplus Met is a biguanide and thiazolidinedione antidiabetic combination. It works by decreasing the amount of sugar the liver produces and the intestines absorb. It also helps to make your body more sensitive to the insulin that you naturally produce.

Missed Dose

If you miss a dose of Actoplus Met , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Storage

Store this medicine at room temperature at 77 degrees F (25 degrees C) in a tightly-closed container, away from heat, moisture, and light. Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted.

Warnings/Precautions

Do NOT use Actoplus Met if:

• you are allergic to any ingredient in Actoplus Met
• you have type 1 diabetes
• you have moderate to severe heart failure
• you have a severe infection, low blood oxygen levels, kidney or liver problems, or high blood ketone or acid levels (eg, diabetic ketoacidosis), or you are severely dehydrated
• you have had a stroke or a recent heart attack, or you are in shock
• you are 80 years old or more and have not had a kidney function test
• you will be having surgery or certain lab procedures
• you have a history of liver problems, including jaundice (yellowing of the skin or eyes), during therapy with a similar medicine called troglitazone

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Actoplus Met . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of heart problems (eg, heart failure), abnormal liver function tests, lung or breathing problems, thyroid problems, stomach or bowel problems (eg, paralysis, blockage), adrenal or pituitary problems, eye or vision problems (eg, macular degeneration), bladder cancer, or lactic acidosis
• if you have fluid retention or swelling problems, vomiting, diarrhea, poor health or nutrition, low blood calcium or vitamin B12 levels, or anemia, or if you are dehydrated
• if you have an infection, fever, recent injury, or moderate to severe burns
• if you have a history of bone fracture, weak bones (eg, osteoporosis), or low calcium intake
• if you drink alcohol or have a history of alcohol abuse
• if you will be having surgery or certain lab procedures
• if you take a beta-blocker (eg, propranolol)

Some MEDICINES MAY INTERACT with Actoplus Met . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Amiloride, cimetidine, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, or vancomycin because they may increase the risk of Actoplus Met ’s side effects
• Calcium channel blockers (eg, nifedipine), corticosteroids (eg, prednisone), diuretics (eg, furosemide, hydrochlorothiazide), estrogen, hormonal contraceptives (eg, birth control pills), insulin, isoniazid, nicotinic acid, oral antidiabetics (eg, glipizide), phenothiazines (eg, chlorpromazine), phenytoin, sympathomimetics (eg, albuterol, pseudoephedrine), or thyroid hormones (eg, levothyroxine) because the risk of high or low blood sugar may be increased
• Gemfibrozil because it may increase the risk of Actoplus Met ’s side effects
• Rifampin because it may decrease Actoplus Met ’s effectiveness, resulting in high blood sugar
• Anticoagulants (eg, warfarin) because their effectiveness may be decreased or the risk of their side effects may be increased by Actoplus Met

Possible Side Effects

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

• Cold-like symptoms; diarrhea; headache; indigestion; mild weight gain; nausea; stomach upset.

Seek medical attention right away if any of these SEVERE side effects occur:

• Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision or other vision changes; bone pain; chest pain or discomfort; dark urine; difficult or painful urination; dizziness or lightheadedness; fainting; fast or difficult breathing; feeling of being unusually cold; general feeling of being unwell; muscle pain or weakness; pale stools; persistent loss of appetite; severe or persistent headache, nausea, or vomiting; shortness of breath; slow or irregular heartbeat; sudden unexplained weight gain; swelling of the hands, ankles, or feet; unusual stomach pain or discomfort; unusual drowsiness; unusual tiredness or weakness; yellowing of the eyes or skin.

More Information

If you have any questions about Actoplus Met , please talk with your doctor, pharmacist, or other health care provider.
Actoplus Met is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.
If using Actoplus Met for an extended period of time, obtain refills before your supply runs out.

ActoPlus Met
		ActoPlus Met 30 pills x 500 mg	$49.83
		ActoPlus Met 60 pills x 500 mg	$87.12
		ActoPlus Met 90 pills x 500 mg	$118.29

	Package	Price	Per Item	Savings	Order
	Avandamet 30 pills x 500 mg	$44.85	$1.5	$0
	Avandamet 60 pills x 500 mg	$77.4	$1.29	$13
	Avandamet 90 pills x 500 mg	$100.17	$1.11	$35

Avandamet
	Avandamet is used for treating type 2 diabetes.

Drug Name

Avandamet (Rosiglitazone/Metformin)

Drug Uses

Avandamet is used for treating type 2 diabetes. It is used along with diet and exercise. It may be used alone or with other antidiabetic medicines.

How to use

Use Avandamet as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Take Avandamet by mouth with meals.
Take Avandamet on a regular schedule to get the most benefit from it. Taking Avandamet at the same time each day will help you remember to take it.
Continue to take Avandamet even if you feel well. Do not miss any doses.

Drug Class and Mechanism

Avandamet is a thiazolidinedione and biguanide antidiabetic combination. It works by decreasing the amount of sugar that the liver produces and the intestines absorb. It also helps to make your body more sensitive to the insulin that you naturally produce.

Missed Dose

If you miss a dose of Zyvox, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Storage

Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture. Brief storage from 59-86 degrees F (15-30 degrees C) is permitted. Do not store in the bathroom. Keep all medicines away from children and pets.

Warnings/Precautions

Do NOT use Avandamet if:

• you are allergic to any ingredient in Avandamet
• you have type 1 diabetes
• you have moderate to severe heart failure
• you have had a severe infection, low blood oxygen levels, kidney or liver problems, high blood ketone or acid levels (eg, diabetic ketoacidosis), or a type of diabetic eye problem (macular edema), or you are severely dehydrated
• you have had a stroke or a recent heart attack, or you are in shock
• you are 80 years old or more and have not had a kidney function test
• you will be having surgery or certain lab procedures
• you have a history of liver problems, including jaundice (yellowing of the skin or eyes), during therapy with a similar medicine called troglitazone
• you are taking a nitrate (eg, nitroglycerin) or using insulin

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Avandamet . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of heart problems (eg, heart failure), abnormal liver function tests, lung or breathing problems, thyroid problems, stomach or bowel problems (eg, paralysis, blockage), adrenal or pituitary problems, eye or vision problems, or lactic acidosis
• if you have fluid retention or swelling problems, vomiting, diarrhea, poor health or nutrition, low blood calcium or vitamin B12 levels, or anemia, or you are dehydrated
• if you have an infection, fever, recent injury, or moderate to severe burns
• if you drink alcohol or have a history of alcohol abuse
• if you will be having surgery or certain lab procedures
• if you are taking a beta-blocker (eg, propranolol)

Some MEDICINES MAY INTERACT with Avandamet . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Insulin or nitrates (eg, nitroglycerin) because the risk of heart problems may be increased
• Amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, or vancomycin because they may increase the risk of Avandamet ’s side effects
• Calcium channel blockers (eg, nifedipine), corticosteroids (eg, prednisone), diuretics (eg, furosemide, hydrochlorothiazide), estrogen, hormonal contraceptives (eg, birth control pills), isoniazid, nicotinic acid, oral antidiabetics (eg, glipizide), phenothiazines (eg, chlorpromazine), phenytoin, sympathomimetics (eg, albuterol, pseudoephedrine), or thyroid hormones (eg, levothyroxine) because the risk of high or low blood sugar may be increased
• Gemfibrozil because it may increase the risk of Avandamet ’s side effects Rifampin because it may decrease Avandamet ’s effectiveness, resulting in high blood sugar
• Anticoagulants (eg, warfarin) because their effectiveness may be decreased or the risk of their side effects may be increased by Avandamet

Check with your doctor if any of these most common side effects persist or become bothersome:

• attention disturbance; blurred vision; changes in weight; clumsiness; constipation; decreased appetite; decreased sex drive; diarrhea; dizziness; drowsiness; dry mouth; flu; headache; impaired coordination/balance; increased salivation; joint pain; lightheadedness; nausea; nervousness; pounding in the chest; rapid heartbeat; restlessness; skin inflammation; sleeplessness; sweating; unsteadiness; unusual weakness; vomiting; weakness.

Seek medical attention right away if any of these severe side effects occur:

• severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); depression; fainting; involuntary movements; memory impairment.

More Information

If you have any questions about Avandamet , please talk with your doctor, pharmacist, or other health care provider.
Avandamet is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.
If using Avandamet for an extended period of time, obtain refills before your supply runs out.

Avandamet
		Avandamet 30 pills x 500 mg	$44.85
		Avandamet 60 pills x 500 mg	$77.4
		Avandamet 90 pills x 500 mg	$100.17

	Package	Price	Per Item	Savings	Order
	Glucotrol XL 60 pills x 10 mg	$41.39	$0.69	$0
	Glucotrol XL 90 pills x 10 mg	$47.7	$0.53	$15

Glucotrol XL
	Glucotrol XL is used for treating type 2 diabetes in patients who cannot control blood sugar levels by diet and exercise alone.

Drug Name

Glucotrol XL (Glipizide)

Drug Uses

Glucotrol XL is used for treating type 2 diabetes in patients who cannot control blood sugar levels by diet and exercise alone. It is used along with diet and exercise. It may be used alone or with other antidiabetic medicines.

How to use

Use Glucotrol XL as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Take Glucotrol XL by mouth with breakfast or the first main meal of the day unless your doctor tells you otherwise. Swallow Glucotrol XL whole. Do not break, crush, or chew before swallowing.
Glucotrol XL works best if it is taken at the same time each day.
Continue to take Glucotrol XL even if you feel well. Do not miss any doses.

Drug Class and Mechanism

Glucotrol XL is a sulfonylurea antidiabetic medicine. It causes the pancreas to release insulin, which helps to lower blood sugar.

Missed Dose

If you miss a dose of Zyvox, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Storage

Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Warnings/Precautions

Do NOT use Glucotrol XL if:

• you are allergic to any ingredient in Glucotrol XL
• you have certain severe problems associated with diabetes (eg, diabetic ketoacidosis, diabetic coma)
• you have moderate to severe burns, or very high blood acid levels (acidosis)
• you have type 1 diabetes
• you are pregnant and are within 1 month of the expected delivery date

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Glucotrol XL. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have had a severe allergic reaction (eg, a severe rash, hives, breathing difficulties, dizziness) to any other sulfonamide medicine, such as acetazolamide, celecoxib, certain diuretics (eg, hydrochlorothiazide), probenecid, sulfamethoxazole, valdecoxib, or zonisamide
• if you have a history of liver, kidney, thyroid, or heart problems
• if you have stomach or bowel problems (eg, stomach or bowel narrowing or blockage, stomach paralysis), drink alcohol, or have had poor nutrition
• if you have very poor health, a high fever, a severe infection, severe diarrhea, or high blood acid levels, or have had a severe injury
• if you have a history of certain hormonal problems (eg, adrenal or pituitary problems, syndrome of inappropriate secretion of antidiuretic hormone [SIADH]), or low blood sodium levels
• if you will be having surgery

Some MEDICINES MAY INTERACT with Glucotrol XL. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Beta-blockers (eg, propranolol) because the risk of low blood sugar may be increased. They may also hide certain signs of low blood sugar and make it more difficult to notice
• Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), anticoagulants (eg, warfarin), azole antifungals (eg, miconazole, ketoconazole), chloramphenicol, clofibrate, fenfluramine, insulin, monoamine oxidase (MAO) inhibitors (eg, phenelzine), nonsteroidal anti-inflammatory medicines (NSAIDs) (eg, ibuprofen), phenylbutazone, probenecid, quinolone antibiotics (eg, ciprofloxacin), salicylates (eg, aspirin), or sulfonamides (eg, sulfamethoxazole) because the risk of low blood sugar may be increased
• Calcium channel blockers (eg, diltiazem), corticosteroids (eg, prednisone), decongestants (eg, pseudoephedrine), diazoxide, diuretics (eg, furosemide, hydrochlorothiazide), estrogens, hormonal contraceptives (eg, birth control pills), isoniazid, niacin, phenothiazines (eg, promethazine), phenytoin, rifamycins (eg, rifampin), sympathomimetics (eg, albuterol, epinephrine, terbutaline), or thyroid supplements (eg, levothyroxine) because they may decrease Glucotrol XL Extended-Release Tablets’s effectiveness, resulting in high blood sugar
• Gemfibrozil because blood sugar may be increased or decreased

Possible Side Effects

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

• Diarrhea; dizziness; gas; nausea.

Seek medical attention right away if any of these SEVERE side effects occur:

• Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; skin redness; dizziness); confusion; dark urine; fainting; fever, chills, or persistent sore throat; irregular heartbeat; low blood sugar symptoms (eg, anxiety, drowsiness, fast heartbeat, headache, lightheadedness, severe or persistent dizziness, tremors, unusual sweating, weakness); severe or persistent blurred vision or other vision problems; unusual bruising or bleeding; unusual tiredness or weakness; yellowing of the eyes or skin.

More Information

If you have any questions about Glucotrol XL, please talk with your doctor, pharmacist, or other health care provider.
Glucotrol XL is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

Glucotrol XL
		Glucotrol XL 60 pills x 10 mg	$41.39
		Glucotrol XL 90 pills x 10 mg	$47.7